Document Type : Research Paper
Authors
Department of Surgery and Obstetrics, College of Veterinary Medicine, University of Al-Qadisiyah, Al-Diwaniyah City, Iraq
10.29079/qjvms.2023.183464
Abstract
The study was designed to investigate the effect of 820 nm laser therapies on skin wound healing in rabbits. Thirty male adult New-Zealand rabbits were utilized and randomly divided into two equal groups (n 15), G1 laser therapy and G2 control groups. Two parallel (right and left) full-thickness skin incisions 2 cm lengths were made on the dorsum of each rabbit at a distance of 3cm from the spine. Incisions were closed by simple interrupted sutures using 4/0 silk suture. The right incisions in G1 were irradiated with pulsed (GaAlAs) laser therapy (820 nm, 8 J/cm2 energy density, and 50 mW power output, for 30 sec. once a day for 3 successive days). Incisions of G2 and the left incisions of G1 were left without treatment as a control. Skin wound specimens were taken from animals of both groups after 3, 7, and 14 days’ post wounding for histopathological evaluation of the healing process. Histopathological examinations demonstrated that wound healing in G1 was promoted such as fast restoration of tissue continuity, improved collagen fiber production, and the reduction of excessive inflammation, while the control group did not. Thus LLLT found to promote the healing of incisional wounds in the present rabbit model, and laser treatment has been beneficial effects during the inflammatory, proliferation, and maturation phases of a wound healing. The 8 J/cm2 energy density of (820 nm) LLLT promote the wound healing, through prevention of excessive inflammation, increased formation of collagen fibers, and recovery in continuity of tissue.
Keywords
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