Authors
1 Unit of Zoonotic Diseases, College of Veterinary Medicine, University of Al-Qadisiyah, Iraq
2 Department of Microbiology and Parasitology, College of Veterinary Medicine, University of Basrah, Iraq
3 Department of Pathology and Poultry Diseases, College of Veterinary Medicine, University of Al-Qadisiyah, Iraq.
Abstract
The current article has been planned to provide highlights on the immune response and itsprotective role in chickens under natural field infection of M. gallisepticum MG that cause tovigorous inflammation in the trachea, lungs, and air sacs. This article will converge on the host immune response to Mycoplasma gallisepticuminfection, also will be clarify a brief illustration of antigenic structure of Mycoplasma spp., andbasic immunological interactions between MG and the host that include innate immunity,adaptive immunity (humoral and cellular immune response), finally will discuss the mostcommon serological tests. Mycoplasma gallisepticum is tenuous living microorganism and the smallest one, canreproduce autonomously, cause world famed disease known as chronic respiratory disease forchicken that led to increased mortality, increased mortality, losing weight and negatively affectsbreeder flocks performance, in addition to the importance of the vertical transmission andprevailing among bird types, thereby it regarded as one of the most worldwide expensive poultrypathogens. Depending on the antigenic structure, and pathogenicity, Mycoplasmas are located invariable clusters, these two features affect the relation between Mycoplasmas and immunesystem, and because the chronic process of infection it may indicate that all immune componentsare involved in the disease pathogenesis as well as pathogenicity Primary confrontation of invading organisms occurs via natural or innate immunity withconsiderable resistance and participates in minimizing the infection progress although theadaptive immunity is critical in both sides as it contributes or has a role in the controlling theinfection alongside with contrast role in the immunopathogenesis. In conclusion the relationship between Mycoplasma gallisepticum and host immune responseis controlled by several factors that elucidated in the present article, which complicate thismutual interaction, thereby the clinical manifestation of MG infection could be differed and theprognosis may be variable.
Keywords
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